Hans Bräuner: search on Z-Library

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1

Synthesis and Structure–Activity Relationships of N -Benzyl Phenethylamines as 5-HT 2A/2C Agonists

Hansen, Martin, Phonekeo, Karina, Paine, James S., Leth-Petersen, Sebastian, Begtrup, Mikael, Bräuner-Osborne, Hans, Kristensen, Jesper L.

Journal:

ACS Chemical Neuroscience

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

2

Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors

Xiong, Xiao-Feng, Zhang, Hang, Underwood, Christina R., Harpsøe, Kasper, Gardella, Thomas J., Wöldike, Mie F., Mannstadt, Michael, Gloriam, David E., Bräuner-Osborne, Hans, Strømgaard, Kristian

Journal:

Nature Chemistry

Year:

2016

Language:

english

File:

PDF, 2.68 MB

english, 2016

3

A New Pathophysiological Aspect of S100B in Schizophrenia: Potential Regulation of S100B by Its Scavenger Soluble RAGE

Johann Steiner, Martin Walter, Michael T. Wunderlich, Hans-Gert Bernstein, Benjamin Panteli, Mareike Brauner, Roland Jacobs, Tomasz Gos, Matthias Rothermundt, Bernhard Bogerts

Journal:

Biological Psychiatry

Year:

2009

Language:

english

File:

PDF, 292 KB

english, 2009

4

Computer-Aided Discovery of Aromatic l -α-Amino Acids as Agonists of the Orphan G Protein-Coupled Receptor GPR139

Isberg, Vignir, Andersen, Kirsten B., Bisig, Christoph, Dietz, Gunnar P. H., Bräuner-Osborne, Hans, Gloriam, David E.

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 256 KB

english, 2014

5

Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists

Hansen, Martin, Jacobsen, Stine Engesgaard, Plunkett, Shane, Liebscher, Gudrun Eckhard, McCorvy, John D., Bräuner-Osborne, Hans, Kristensen, Jesper Langgaard

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 517 KB

english, 2015

6

Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer

Jacobsen, Stine Engesgaard, Gether, Ulrik, Bräuner-Osborne, Hans

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

7

Identification of a novel scaffold for a small molecule GPR139 receptor agonist

Nøhr, Anne Cathrine, Shehata, Mohamed A., Palmer, Daniel, Pokhrel, Rina, Vallianou, Maria, Foster, Simon R., Gentry, Patrick R., Gloriam, David E., Bräuner-Osborne, Hans

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 2.45 MB

english, 2019

8

Ligands for Glutamate Receptors: Design and Therapeutic Prospects

Bräuner-Osborne, Hans, Egebjerg, Jan, Nielsen, Elsebet Ø., Madsen, Ulf, Krogsgaard-Larsen, Povl

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 1.48 MB

english, 2000

9

New Equipment for Neuromuscular Transmission Monitoring: A Comparison of the TOF-Guard with the Myograph 2000

Hans Kirkegaard-Nielsen, Hans Søren Helbo-Hansen, Peter Lindholm, Henrik Stougaard Pedersen, Inge Krogh Severinsen, Michael Braüner Schmidt

Journal:

Journal of Clinical Monitoring and Computing

Year:

1998

File:

PDF, 1.57 MB

1998

10

Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D

Hans Bräuner-Osborne, Anders A Jensen, Paul O Sheppard, Birger Brodin, Povl Krogsgaard-Larsen, Patrick O’Hara

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2001

Language:

english

File:

PDF, 837 KB

english, 2001

11

Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139

Shehata, Mohamed A., Nøhr, Anne C., Lissa, Delphine, Bisig, Christoph, Isberg, Vignir, Andersen, Kirsten B., Harpsøe, Kasper, Björkling, Fredrik, Bräuner-Osborne, Hans, Gloriam, David E.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.16 MB

english, 2016

12

Specific γ-hydroxybutyrate-binding sites but loss of pharmacological effects of γ-hydroxybutyrate in GABAB(1)-deficient mice

Klemens Kaupmann, John F. Cryan, Petrine Wellendorph, Cedric Mombereau, Gilles Sansig, Klaus Klebs, Markus Schmutz, Wolfgang Froestl, Herman Van Der Putten, Johannes Mosbacher, Hans Bräuner-Osborne, P

Journal:

European Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 443 KB

english, 2003

13

The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid

Rasmus P. Clausen, Kasper B. Hansen, Patrizia Calí, Birgitte Nielsen, Jeremy R. Greenwood, Mikael Begtrup, Jan Egebjerg, Hans Bräuner-Osborne

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

14

Differential Compartmentalization and Distinct Functions of GABAB Receptor Variants

Réjan Vigot, Samuel Barbieri, Hans Bräuner-Osborne, Rostislav Turecek, Ryuichi Shigemoto, Yan-Ping Zhang, Rafael Luján, Laura H. Jacobson, Barbara Biermann, Jean-Marc Fritschy, Claire-Marie Vacher, Ma

Journal:

Year:

2006

Language:

english

File:

PDF, 833 KB

english, 2006

15

( S )-Homo-AMPA, a Specific Agonist at the mGlu 6 Subtype of Metabotropic Glutamic Acid Receptors

Ahmadian, Haleh, Nielsen, Birgitte, Bräuner-Osborne, Hans, Johansen, Tommy N., Stensbøl, Tine B., Sløk, Frank A., Sekiyama, Naohiro, Nakanishi, Shigetada, Krogsgaard-Larsen, Povl, Madsen, Ulf

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 161 KB

english, 1997

16

(1 S , 3 S )-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid ( CPP-115 ), a Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine Addiction

Pan, Yue, Gerasimov, Madina R., Kvist, Trine, Wellendorph, Petrine, Madsen, Karsten K., Pera, Elena, Lee, Hyunbeom, Schousboe, Arne, Chebib, Mary, Bräuner-Osborne, Hans, Craft, Cheryl M., Brodie, Jona

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.03 MB

english, 2012

17

Introduction to Special Issue in Honor of Professor Povl Krogsgaard-Larsen

Bräuner-Osborne, Hans, Schousboe, Arne

Journal:

Neurochemical Research

Year:

2014

Language:

english

File:

PDF, 179 KB

english, 2014

18

Known regulators of nitric oxide synthase and arginase are agonists at the human G-protein-coupled receptor GPRC6A

Bolette Christiansen, Petrine Wellendorph, Hans Bräuner-Osborne

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 181 KB

english, 2006

19

Design, Synthesis, and Pharmacological Characterization of Novel, Potent NMDA Receptor Antagonists

Conti, Paola, De Amici, Marco, Grazioso, Giovanni, Roda, Gabriella, Barberis Negra, Federico F., Nielsen, Birgitte, Stensbøl, Tine B., Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla, De Sarro,

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

20

Neue Synthesen für azavinyloge Amidacetale

Kantlehner, Willi, Haug, Erwin, Speh, Peter, Bräuner, Hans-Jürgen

Journal:

Year:

1985

File:

PDF, 148 KB

1985

21

Pharmacology and function of the orphan GPR 139 G protein‐coupled receptor

Vedel, Line, Nøhr, Anne Cathrine, Gloriam, David E., Bräuner‐Osborne, Hans

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2019

File:

PDF, 673 KB

2019

22

Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline

Henrik Pedersen, Hans Bräuner-Osborne, Richard G. Ball, Karla Frydenvang, Eddi Meier, Klaus P. Bøgesø, Povl Krogsgaard-Larsen

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 415 KB

english, 1999

23

Biased agonism of the calcium-sensing receptor

Alex Rojas Bie Thomsen, Maja Hvidtfeldt, Hans Bräuner-Osborne

Journal:

Year:

2012

Language:

english

File:

PDF, 501 KB

english, 2012

24

Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor

Petrine Wellendorph, Hans Bräuner-Osborne

Journal:

Year:

2004

Language:

english

File:

PDF, 1.48 MB

english, 2004

25

Synthesis, Binding Affinity at Glutamic Acid Receptors, Neuroprotective Effects, and Molecular Modeling Investigation of Novel Dihydroisoxazole Amino Acids †

Conti, Paola, De Amici, Marco, Grazioso, Giovanni, Roda, Gabriella, Pinto, Andrea, Hansen, Kasper Bø, Nielsen, Birgitte, Madsen, Ulf, Bräuner-Osborne, Hans, Egebjerg, Jan, Vestri, Valentina, Pellegrin

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 435 KB

english, 2005

26

N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization

Nørskov-Lauritsen, Lenea, Jørgensen, Stine, Bräuner-Osborne, Hans

Journal:

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

27

Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method

Frandsen, Ida Osborn, Boesgaard, Michael W., Fidom, Kimberley, Hauser, Alexander S., Isberg, Vignir, Bräuner-Osborne, Hans, Wellendorph, Petrine, Gloriam, David E.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.50 MB

english, 2017

28

Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors

Roszko, Kelly L., Bi, Ruiye, Gorvin, Caroline M., Bräuner-Osborne, Hans, Xiong, Xiao-Feng, Inoue, Asuka, Thakker, Rajesh V., Strømgaard, Kristian, Gardella, Thomas, Mannstadt, Michael

Journal:

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

29

A Physically Anchored Linkage Map of Pig Chromosome 1 Uncovers Sex- and Position-Specific Recombination Rates

Hans Ellegren, Bhanu P. Chowdhary, Merete Fredholm, Bjørn Høyheim, Maria Johansson, Paul Bräuner Nielsen, Preben D. Thomsen, Leif Andersson

Journal:

Year:

1994

File:

PDF, 693 KB

1994

30

Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors

Hans Bräuner-Osborne, Birgitte Nielsen, Povl Krogsgaard-Larsen

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 186 KB

english, 1998

31

Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor

Clemmensen, Christoffer, Jørgensen, Christinna V., Smajilovic, Sanela, Bräuner-Osborne, Hans

Journal:

Diabetes, Obesity and Metabolism

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

32

The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway

Jacobsen, Stine Engesgaard, Ammendrup-Johnsen, Ina, Jansen, Anna Mai, Gether, Ulrik, Madsen, Kenneth Lindegaard, Bräuner-Osborne, Hans

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 3.39 MB

english, 2017

33

Design of novel conformationally restricted analogues of glutamic acid

Paola Conti, Marco De Amici, Gabriella Roda, Giulio Vistoli, Tine Bryan Stensbøl, Hans Bräuner-Osborne, Ulf Madsen, Lucio Toma, Carlo De Micheli

Journal:

Year:

2003

Language:

english

File:

PDF, 373 KB

english, 2003

34

Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist

Ulf Madsen, Frank A Sløk, Tine B Stensbøl, Hans Bräuner-Osborne, Hans-Christian H Lützhøft, Miguel V Poulsen, Lisbeth Eriksen, Povl Krogsgaard-Larsen

Journal:

European Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

35

2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

Tommy N. Johansen, Yves L. Janin, Birgitte Nielsen, Karla Frydenvang, Hans Bräuner-Osborne, Tine B. Stensbøl, Stine B. Vogensen, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

36

White matter lesions and soluble interleukin-1 receptor type II in CSF from demented and non-demented subjects

Lena Bronge, Lars-Olof Wahlund, Annelie Brauner, Hans Basun, Anita Garlind

Journal:

Neurochemistry International

Year:

2002

Language:

english

File:

PDF, 112 KB

english, 2002

37

Ein neues Herstellungsverfahren für 2,2,2-Trialkoxyacetonitrile und 2-Dialkylamino-2-alkoxycarbonsäurenitrile

Kantlehner, Willi, Haug, Erwin, Frick, Wendelin, Speh, Peter, Bräuner, Hans-Jürgen

Journal:

Year:

1984

File:

PDF, 213 KB

1984

38

Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the G q Protein

Zhang, Hang, Xiong, Xiao-Feng, Boesgaard, Michael W., Underwood, Christina R., Bräuner-Osborne, Hans, Strømgaard, Kristian

Journal:

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

39

Pharmacology of (S)-homoquisqualic acid and (S)-2-amino-5-phosphonopentanoic acid [(S)-AP5] at cloned metabotropic glutamate receptors

Hans Bräuner-Osborne, Povl Krogsgaard-Larsen

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 316 KB

english, 1998

40

The rat GPRC6A: Cloning and characterization

Petrine Wellendorph, Nicole Burhenne, Bolette Christiansen, Bettina Walter, Hartwig Schmale, Hans Bräuner-Osborne

Journal:

Year:

2007

Language:

english

File:

PDF, 611 KB

english, 2007

41

Molecular pharmacology of human NMDA receptors

Maiken Hedegaard, Kasper B. Hansen, Karen T. Andersen, Hans Bräuner-Osborne, Stephen F. Traynelis

Journal:

Neurochemistry International

Year:

2012

Language:

english

File:

PDF, 964 KB

english, 2012

42

Chemoenzymatic Synthesis of a Series of 4-Substituted Glutamate Analogues and Pharmacological Characterization at Human Glutamate Transporters Subtypes 1−3

Alaux, Sebastien, Kusk, Mie, Sagot, Emanuelle, Bolte, Jean, Jensen, Anders A., Bräuner-Osborne, Hans, Gefflaut, Thierry, Bunch, Lennart

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 379 KB

english, 2005

43

Orthoamide und Iminiumsalze, XCIII. Darstellung und Umsetzungen eines vinylogen Orthoamid-Derivats der Kohlensäure mit CH2-aciden Verbindungena

Vettel, Markus, Bräuner, Hans-Jürgen, Kantlehner, Willi

Journal:

Zeitschrift für Naturforschung B

Year:

2018

File:

PDF, 657 KB

2018

44

Allosteric Modulation of the Calcium-Sensing Receptor

Jensen, Anders, Brauner-Osborne, Hans

Journal:

Current Neuropharmacology

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

45

Selective allosteric antagonists for the G protein-coupled receptor GPRC6A based on the 2-phenylindole privileged structure scaffold

Johansson, Henrik, Boesgaard, Michael Worch, Nørskov-Lauritsen, Lenea, Larsen, Inna, Kuhne, Sebastiaan, Gloriam, David E., Bräuner-Osborne, Hans, Sejer Pedersen, Daniel

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 919 KB

english, 2015

46

Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression

Krzywkowski, Karen, Jensen, Anders A., Connolly, Christopher N., Bräuner-Osborne, Hans

Journal:

Pharmacogenetics and Genomics

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

47

Human GIP(3-30)NH 2 inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

Gabe, Maria Buur Nordskov, Sparre-Ulrich, Alexander Hovard, Pedersen, Mie Fabricius, Gasbjerg, Lærke Smidt, Inoue, Asuka, Bräuner-Osborne, Hans, Hartmann, Bolette, Rosenkilde, Mette Marie

Journal:

Biochemical Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.98 MB

english, 2018

48

3-Pyrazolone analogues of the 3-isoxazolol metabotropic excitatory amino acid receptor agonist homo-AMPA. Synthesis and pharmacological testing

Diane Zimmermann, Yves Louis Janin, Lotte Brehm, Hans Bräuner-Osborne, Bjarke Ebert, Tommy Nørskov Johansen, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

European Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 156 KB

english, 1999

49

A new structural class of subtype-selective inhibitor of cloned excitatory amino acid transporter, EAAT2

Hans Bräuner-Osborne, Mette B Hermit, Birgitte Nielsen, Povl Krogsgaard-Larsen, Tommy N Johansen

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 81 KB

english, 2000

50

The dance of the clams: twists and turns in the family C GPCR homodimer

Anders A Jensen, Jeremy R Greenwood, Hans Bräuner-Osborne

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 335 KB

english, 2002

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